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ANTIGEN, CD105
Descriptors Found:
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DeCS
Descriptor
English
:
Endoglin
Descriptor
Spanish
:
Endoglina
Descriptor
Portuguese
:
Endoglina
Synonyms
English
:
CD105 Antigen
Endoglin Protein
Antigen, CD105
Tree Number:
D12.776.543.750.250
D23.050.301.264.035.294
D23.101.100.110.296
Definition
English
:
A membrane glycoprotein and ANGIOGENESIS FACTOR that is expressed by cells of the VASCULAR
ENDOTHELIUM
; VASCULAR SMOOTH MUSCLE; and
MONOCYTES
. It functions as a co-receptor for
TRANSFORMING GROWTH FACTOR BETA
and modulates
CELL ADHESION
.
Mutations
in the
endoglin
gene are associated with cases of HEREDITARY HEMORRHAGIC TELANGIECTASIA.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Record Number:
56643
Unique Identifier:
D000071063
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS